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IPT Low Dose Chemotherapy

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For patients with the following conditions: poor health, cannot tolerate adverse reaction to conventional chemotherapy, not responsive to conventional chemotherapy and refusal to accept conventional chemotherapy, IPT low dose chemotherapy is an effective option. It has minimal toxic side effects, low drug resistance, and is reliable and effective. As reported, IPT low dose chemotherapy has already been widely used for decades with an volumes of pertinent literatures and reports.

What is IPT low dose chemotherapy?
IPT (Insulin Potentiation Therapy) also called IPTLD (Insulin Potentiation Therapy Low Dose Chemotherapy): A kinder, gentler chemotherapy treatment option with significantly less side effects

 

Treatment Mechanism of IPT
FACT: More than 50% of people who receive conventional chemotherapy will die from the side effects of the chemotherapy, NOT from the cancer itself.

All cells, including cancer cells, need fuel (glucose) to “burn” in order to produce the energy necessary for its survival. Insulin molecules act like keys, which open the glucose doorways allowing the glucose to enter the cells. If there is no insulin around, glucose just keeps circulating in the blood and cannot get into the cells. This is the problem that people with Type 1 Diabetes have. Keep in mind that all keys need a lock to turn in, in order to work. The “locks” on the surface of cells are called, insulin receptors.

Cancer cells have developed a very simple and quite effective strategy to assure they get enough fuel in order to survive. They grow many extra insulin receptors on their surfaces in order to attract and utilize more of the circulating glucose (fuel) than the other non-cancerous cells in the body. 

One of the major distinctions between cancer cells and normal cells is that cancer cells have lost the ability to use oxygen when they are “burning” glucose to produce energy. They must resort to a very primitive and inefficient, default method of energy production called glycolysis or fermentation, much like yeast, certain bacteria and other primitive organisms. As a result, they need, at least, 19 times more glucose than normal cells just to survive.

So whether one eats a banana, pasta, bread or a candy bar, the cancer is fed first and the rest of the cells get whatever that is left.

We use this knowledge to target the cancer cells with cytotoxic (cell-killing) agents (chemotherapy drugs). By administering small amounts of insulin prior to the person eating that day, we are able to select the cancer cells from amongst all the other cells in the body because they are able to bind the insulin much more quickly, resulting in what is known as the “therapeutic window” (cancer cells are permeable while the other, normal cells are still hard and impermeable). There are a multitude of effects upon cells when insulin binds to them and one of these effects is that the cells become more permeable (creating openings) by stimulating an enzyme known as delta-9 desaturase. Once the cancer cells have been targeted by the insulin to open their doors, we then administer small amounts of the appropriate chemotherapeutic drugs, from 5% to 10% of the standard dose. Much of what we administer becomes absorbed into the cancer cells rather quickly and not into the normal cells because they are still relatively hard or impermeable. IPT, therefore, is able to take advantage of the powerful cyto-toxic effects of standard chemotherapy without having to use high doses.

Since the dosage is low, side effects are minimized and the treatments can be given more frequently. This gives cancer cells less time to become resistant to the drugs and they can become eliminated in a much shorter time frame.  This is accomplished while sparing the other normal cells in the body from being equally exposed to these toxins; hence, there are very limited “side effects”. One essential consequence is that the immune system is relatively spared from being damaged so that it can continue to defend the body from the cancer. This allows the immune system to protect the body from other cancers that may be “brewing” AND it can also continue to defend against any other possible intrusions, such as micro-organisms (which cause infection and extraneous), chemical poisons, EMFs, radiation and internally derived poisons from accumulated waste.

Practicing IPT
It is easy to manipulate the immediate environment around the cancer cells by having a person not eat for about 6 to 12 hours prior to treatment. A small, calculated dose of insulin is administered and after about 20 to 40 minutes, most of the insulin receptors on the cancer cells are saturated, leaving them permeable. Once this occurs, a small (5-10%) dose of the appropriate chemotherapeutic drug is administered and becomes preferentially taken up by the cancer cells. IPT fits for all cancer patients with the score of 0-2 in PS Score, especially patients who refuse to accept high doses of chemo drugs after multiple conventional chemotherapies. Before practicing IPT, insulin is used to keep the patient’s blood sugar in a low level, normally at around 3.6mmol/L. The insulin reacts through the second messenger system, especially protein tyrosine kinase and it gets more chemo drugs to enter the cancer cells, so as to kill more cancer cells with less chemo drugs. It enhances the therapeutic effect with less toxic adverse reactions. Out-of-body researches showed that some chemo drugs such as methylaminopterin has 10,000 times of an effect after the application of insulin. Compared to conventional chemotherapy, IPT has much less adverse reactions, but doctors should still pay attention to adverse reactions like hyper-sensitiveness and bone marrow depression.

Advantages of IPT
Compared to conventional chemotherapy, insulin is nature’s ‘bow’ that allows us to aim straight into the target” (cancer cells). IPT has the characteristic of low dose and high effects. It reduces the dose of chemo drugs while serving the purpose of killing cancer with accuracy and reduces the damage to normal cells in the human body. These characteristics give IPT wider anti-cancer spectrum, and thus improve its repeatability and most importantly tolerance of the patient. 






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