Nasopharyngeal Carcinoma with Bone Metastases
39 year old male patient, was admitted to Clifford Hospital on Jan 4, 2007. Over 2 years ago, patient underwent chemoradiotherapy for nasopharyngeal carcinoma”. On admission, he complained of headaches, thirst, dry mouth and throat, swelling and aching of gums, swelling pain in cheeks, hearing loss, mental fatigue, and anorexia. ECT examination showed nasopharyngeal carcinoma with skull metastasis. 

Diagnosis: nasopharyngeal carcinoma accompanied with bone metastases after chemoradiotherapy (Ⅳ stage).

Patient was given intravenous nutrition, acupuncture, TCM and medical ozone therapy after admission to the hospital. At the same time, local hyperthermia was given to the nasopharynx. After 1 week, his symptoms of headache, mental fatigue and anorexia improved. Chemotherapy and radiotherapy followed. Simultaneously, whole body hyperthermia and local hyperthermia were conducted. TCM and acupuncture treatment accompanied chemoradiotherapy during the entire process. After 2 months of treatment, the symptoms of dry mouth, swelling and pain of gums disappeared. His hearing was slightly restored and a weight gain of 3 kg was reported.

After discharge, patient persisted with herbal medicine and received non-toxic integrative treatment regularly. After 7 months, re-examination on CT  showed lesions disappeared. ECT showed the skull metastasis of nasopharyngeal carcinoma with no significant change compared with the previous scan. No new metastases was found. Patient continued with regular follow up visits. His condition remained stable and with no recurrence or new incidents of metastases. 

Gastric Cancer with Metastases at the Right Lobe o Liver, Pancreas and Lymph Node
56 year old female patient, was admitted on Dec 29, 2006 to Clifford Hospital. Patient suffered “epigastric pain with melena for the past year. Her condition worsened for 1 week”. 

Diagnosis:Gastric adenocarcinoma with intermediate differentiation accompanied with multiple metastases at the right lobe of liver, pancreas, retroperitoneal lymph node.

Patient was transferred to Oncology Department of Clifford Hospital for further treatment as patient was unable to undergo surgery. She lost 10 kg of weight over the past 8 months. She had moderate anemia and in poor physical condition when she was admitted. Blood transfusion was immediately given for anemia; PTN was prescribed boost nutrition; acid prevention, gastric mucosa protection to prevent bleeding. The course of treatment included whole body hyperthermia, peritoneal perfusion, chelation detoxification, nutrition, medical ozone, TCM, acupuncture and medical Qigong therapy. After 5 week of treatment, patient’s condition was improved markedly. Hemoglobin was stabilized at about 95g/L.

Patient was hospitalized for 81 days. After integrative treatment, patient show significant improvement in her mental state, appetite, sleep, normal urine and stool. There was no further nausea, vomiting, and abdominal pain. Weight increased by 12kg and maintained at 56kg. Hemogram returned to normal, and anemia improved. 

Pancreatic Carcinoma with Liver Metastasis Lymph and Node Metastasis
Canadian male patient, was admitted on Sept 4, 2007 to Clifford Hospital for abdominal pain, anorexia, and weight loss for more than 2 months”. He had surgery one year ago for pancreatic carcinoma. In July 2007. Patient exhibited recurrent abdominal dull pain, accompanied with anorexia, obviously thin physique with weight loss of 8kg. He came to Clifford Hospital from Canada for further investigation and treatment.

Diagnosis: Postoperative pancreatic carcinoma recurrence, accompanied with lymph node metastasis and liver metastasis.

When the patient was admitted, the symptoms were poor appetite, weight loss and pain. However, his mental state was reasonably positive. Patient was supplemented with trypsin in combination with medicated diet. Whole body medium-high temperature hyperthermia, chelation detoxification and EBOO were conducted alternatively. Herbal medicine and acupuncture treatment were administered throughout the treatment.

After the patient was hospitalized for 45 days of integrative treatments, his mental state improved, pain relieved, food intake was normal, body weight had increased to 56kg. His quality of life was significantly improved. He participated in regular recreational activities and the Karnofsky performance score was 90. The patient was reassessed 2 months after hospitalization by abdominal CT. Results show no recurrence of lesions in the residual pancreas, and at the head of the pancreas, the number of multiple intrahepatic low-density lesions had not increase, the size reduced compared to before admission.

Patient continued to adhere to outpatient treatment, during which chelation detoxification therapy was given twice a week, medical ozone therapy once a week, and hyperthermia once a week. Patient was followed after 5 months. Abdominal CT show postoperative liver metastases of pancreatic carcinoma. The number of liver metastases had decreased and the volume was also reduced; blood routine was normal; Tumor markers were normal. Patient returned to a normal life free from any discomfort. He remained on a weekly outpatient treatment program.

Colon Cancer with Hepatic Metastases
53 year old male patient, was admitted on June 28, 2006 to Clifford Hospital for “postoperative colon cancer for more than 2 years, 9 months after interventional chemotherapy for liver metastases and abdominal pain for 2 weeks”.

Diagnosis: Hepatic metastases after surgery of colon cancer.

After patient was admitted and a comprehensive assessment was completed,  non-toxic integrative treatment in combination of Irinotecan + Erbitux was recommended. Patient refused chemotherapy and bio-targeted therapy. He chose nontoxic integrative treatment. Chelation detoxification, local hyperthermia, EBOO were conducted in combination with TCM and acupuncture therapy.

Although the patient was diagnosed with hepatic metastasis of advanced colonic carcinoma on admission, he had no obvious symptoms. Patient was hospitalized for 97 days with had no obvious discomfort during the application of green comprehensive treatment. After treatment, patient’s mental state was positive, right upper abdominal pain disappeared, diet was normal and he slept well. Patient returned as outpatient for double application each of chelation detoxification, medical ozone, local hyperthermia, and acupuncture treatments, every 20 days after discharge, and was prescribed herbal medicine. Abdominal CT for 3 months after discharge showed that intrahepatic metastases had decreased and no new lesions were found.

Patient was followed for 2 years and 8 months after discharge. His condition remained stable. He continued with regular outpatient treatments and reviews.

Systemic Multiple Bone Metastatic Tumors
73 year old male patient was admitted on Feb 08, 2009 to Clifford Hospital due to “weight loss for more than 1 year accompanied with anorexia and multiple physical pain for 3 months”. Patient experienced weight loss spontaneously in January 2008. He was not bothered by any fever, night sweats, palpitations, excessive dreams, polydipsia, polyphagia or polyuria, abdominal pain, diarrhea or other symptoms at the onset of the disease. Patient underwent endoscopy in another hospital, suggesting chronic gastritis, which was left untreated. Patient had gradually lost about 40kg of weight during the period of 1 year after the onset of the disease (from 110kg to 70 kg). 3 months before admission, patient exhibited non-incentive anorexia and multiple physical pain (severe at the chest and waist). He took morphine sulfate sustained-release tablets of 150mg/time, once every 12 hours for pain relief. He suffered shortness of breath, fatigue, weakness of lower limb mild pitting edema. He exhibited no blurred vision, palpitations, chest pain or tightness, lower limb joint swelling, or varicose veins. He had acceptable (register average number of hours sleep would be revealing?) sleep, poor appetite, normal urine and stool. The patient was admitted as Outpatient due to “weight loss with unknown cause”.

Physical examination: No obvious positive signs in heart-lung-abdomen; bilateral ribs, thoracic and lumbar multiple vertebral spinous process tenderness and percussion pain.

Auxiliary examinations: Blood routine show: normal blood routine, normal liver and kidney function, rheumatoid and immunologic indexes, and normal 6 items of diabetes. The five tumor markers show: CA199 92.75ng/ml and others were normal. PET-CT show: glucose metabolism was increased at left ribs 4,6,11, 11 thoracic vertebrae, right pubis and ischium; possible metastasis; T11 vertebral pathological fracture. No abnormalities were found by gastrointestinal endoscopy. Results of bone marrow aspiration and biopsy were normal.

Diagnosis: Systemic multiple bone metastatic tumors.

Integrative treatments: Multiple bone metastases was diagnosed by imaging. Since patient was unfit for surgery and chemoradiotherapy, hyperthermia-based comprehensive treatment was conducted to achieve the best result. Whole body medium-low temperature hyperthermia was given, once every 2 weeks; local hyperthermia at the right hip, once every other day; and systematic biofeedback therapy, 3 times a week. At the same time, chelation detoxification was given. EBOO was given twice a week. Herbal medicine and acupuncture were prescribed throughout the treatment. The patient showed pale and plump tongue, white and slippery tongue fur, and slow and deep pulse which belonged to the syndromes of Ying-cold coagulation, and obstruction of collaterals by blood stasis. The treatment focused on warming Yang to expel coldness as well as promoting blood circulation to remove meridian obstruction.

Medication: The prescription recommended was Yanghe Decoction. Specific medication: Radix Rehmanniae Preparata 30g, Ramulus Cinnamomi 10g, Radix Aconiti preparata (Predecoct) 6g, Deer-horn Gelatin (smelt) 15g, Asarum 3g, Seed of Brassica Alba 10g, Fructus Psoraleae 15g, Ephedra 3g, Speranskia Tuberculata 15g, Angelica Sinensis 10g, Clematis Chinensis Osbeck 20g, and Glycyrrhiza Uralensis 6g, one dose a day, decocted with water for oral administration.

Acupuncture on acupoints: Juegu, Taixi, Sanyinjiao, Zusanli, Geshu, Xuehai, Linggu, Dabai and Waisanguan. Method: Used mild reinforcing-reducing method. Retained the needle for 20 minutes, once per day. Took 2 days off after 5 times of acupuncture.

Moxibustion on acupoints: Dazui, Zusanli, Shenzhu, Mingmen, Pishu and Shenshu. Methods: Took 2 points each time with a moxa stick for moxibustion. Conducted moxibustion for 10 minutes above each point, once per day. Took 2 days off after 5 times of moxibustion.

Auricular acupoints: Subcortex, Jiaogan, Shenmen, Zhen, Adrenal Gland, Kidney, Pishu, Stomach and Erjian. Methods: Adhere cowherb seed to auricular points . Patient was asked to apply pressure to the points 3 to 5 times every day and press each point for 3 to 5 minutes, twice a week, alternating ears.

Treatment outcome: Patient was hospitalized for 59 days. Symptoms of whole body bone pain disappeared after treatment without analgesic. With a normal appetite, his weight was kept at 70kg. There was no obvious discomfort. Patient walked independently and could manage self care. Karnofsky performance score was 90. PET-CT was done 3 months later and glucose metabolism was reduced. CA199 10ng/ml was normal. Patient continued with outpatient treatment of chelation detoxification twice a week; EBOO twice a week; local hyperthermia twice a week,; systematic biofeedback therapy 3 times a week; and whole body medium-low temperature hyperthermia once a month for 3 consecutive months. PET-CT was periodically done and no new lesions found. Follow-up had been conducted for over 4 years, whenever patient complained of pain or discomfort.