Zhao Changlin, et al.
Clifford Hospital, Oncological Integrative Treatment Center
Publication: Journal of Practical Traditional Chinese Internal Medicine
Abstract:To observe the effect of Shugan Jianpi Decoction combining Jiedu Kangai Decoction on human liver cancer cell strain HpG2, IL-6 and IGF-IR. MMT, IL-6 ELISA and IGF-TR ELISA were tested after 24h, 48h, 72h, and 96h of co-cultivation of Shugan Jianpi Decoction, Jiedu Kangai Decoction and HpGa cell strain. C-DDP was used in Control Group. As a result, depression rate of MMT was 11.1%, depression rate of Jiedu Kangai Decocion was 72.8%, and depression rate of C-DDP was 74.7%. On comparison of Shugan Jianpi Decoction and Jiedu Kangai Decoction, P=0.000. On comparison of C-DDP and HpG2, P＜0.01. On comparison of Jiedu Kangai Decoction and HpG2, P＜0.01. On comparison of Shugan Jianpi Decoction and HpG2, P＞0.05. On Comparison of IGF-IR, C-DDP and HpG2, P＜0.01. On comparison of Jiedu Kangai Decoction and HpG2, P＜0.01. The effects of Shugan Jianpi Decoction and Jiedu Kangai Decoction on HpG2 cell strain are different.
Keywords: Shugan Jianpi Decoction; Jiedu Kangai Decoction; HpG2, IL-6, IGF-IR, Randomized Parallel Control Study
